Unraveling the Weighty Enigma: Exploring the Intricate Relationship between Obesity and Intracerebral Hemorrhage

Introduction: Obesity is a global health concern with significant implications for various medical conditions, including cerebrovascular diseases. Intracerebral hemorrhage (ICH), characterized by bleeding within the brain parenchyma, is a severe form of stroke. While obesity is linked to an increased risk of cardiovascular diseases, its specific relationship with ICH is not well understood. This study aims to explore how obesity influences the incidence, severity, and outcomes of ICH.

Methodology: A retrospective cohort study was conducted at D.Y. Patil Medical College, and Hospital Kolhapur, from 2019-2023. The cohort included 500 ICH patients, with detailed clinical and demographic data collected. Statistical analyses, including logistic regression and survival analysis, assessed the relationship between obesity and ICH incidence, severity, short-term survival, and long-term outcomes.

Results: Obesity was significantly associated with an increased incidence of ICH. Interestingly, obese patients showed a short-term survival advantage, with lower mortality rates in the weeks following ICH. However, this benefit diminished over time, with no significant differences in long-term outcomes across BMI categories. Obese patients did not exhibit greater ICH severity or complications compared to non-obese patients.

Conclusion: Obesity is associated with an increased risk of ICH and a paradoxical short-term survival advantage. However, this benefit fades over time, emphasizing the need for continued monitoring and tailored interventions in obese ICH patients.