Karai, Oumaima and Aouine, Younas and Alami, Anouar and Faraj, Hassane and Hallaoui, Abdelilah El (2020) Synthesis, Characterization and Antibacterial Activity of Methyl N-[1-(benzoylamino)-2-methoxy-2- oxoethyl]Tryptophanate. In: Theory and Applications of Chemistry Vol. 4. B P International, pp. 133-141. ISBN 978-93-89816-29-7
Full text not available from this repository.Abstract
The title compound, methyl N-[1-(benzoylamino)-2-methoxy-2-oxoethyl]tryptophanate 2, have been
synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate with methyl
2-amino-3-(1H-indol-3-yl)propanoate in acetone, with the presence of diisopropylethylamine as a
base. The structure of the prepared compound was characterized by 1H, 13C NMR in addition to MS,
X-Ray diffraction data, and elemental analysis. This compound was tested in vitro for its antibacterial
activity against Gram-positive bacteria, Bacillus subtilis and Staphylococcus aureus, and Gramnegative
bacteria, Escherichia coli, Pseudomonas aeruginosa and Salmonella enteric. The MIC
values showed that the synthesized compound had a bactericidal effect against the strains tested.
| Item Type: | Book Section |
|---|---|
| Subjects: | Eprints AP open Archive > Chemical Science |
| Depositing User: | Unnamed user with email admin@eprints.apopenarchive.com |
| Date Deposited: | 27 Nov 2023 04:38 |
| Last Modified: | 27 Nov 2023 04:38 |
| URI: | http://asian.go4sending.com/id/eprint/1689 |
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