THE NATURALLY AVAILABLE PHYTO-PRODUCTS OF INDIAN MEDICINAL PLANTS AGAINST ADULTICIDAL ACTIVITY OF HUMAN VECTOR MOSQUITOES

Globally, most of the research community’s consideration for the control of vectors has moved from synthetic chemical pesticides to naturally available phyto-products. In the present investigation, we attempted to evaluate the bio efficacy of various floral extracts and its derived major phyto-compounds against adulticidal activity with different concentrations against the adults of medically important vector mosquitoes Aedes aegypti and Culex quinquefasciatus. The major phyto-chemical compounds of N. brachiata, L. crustacea and O. corniculata leaf extracts were analyzed with GC and Mass Spectroscopy. N. brachiata leaf methanol extract had a total of 10 bio-active compounds acquiring 100% and the major bio-active compounds were 1,4-benzenedicarboxylic acid, bis(2-ethylhexyl) ester (31.03%) and phthalic acid, hexadecyl 2,3,4,5-tetrafluorobenzyl ester (1.86%). Therefore, L. crustacea leaf methanol extract had a total of 10 bio-active compounds acquiring 100% and the major bio-active compounds were 2-acetylamino-2-cyano-acetamide (22.3%) and Phosphorin, 2,4,6-tris(1,1-dimethylethyl)- (28.96%). Similarly, O. corniculata leaf methanol extract had a total of 15 bio-active compounds acquiring 100% and the major bio-active compounds were Succinic acid, 2-methylpent-3-yl pentafluorophenyl ester (18.95%) and 1,2-Cyclohexanedicarboxylic acid, di(2-fluorophenyl) ester (19.91%). The efficacies of the phyto-products were assessed under laboratory conditions. The LC50/ LC90 values of leaf methanol extracts of N. brachiata, L. crustacea and O. corniculata and its derived major phyto-compounds 1,4-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester, Phthalic acid, hexadecyl 2,3,4,5-tetrafluorobenzyl ester, 2-Acetylamino-2-cyano-acetamide, Phosphorin, 2,4,6-tris(1,1-dimethylethyl)-, Succinic acid, 2-methylpent-3-yl pentafluorophenyl ester and 1,2-Cyclohexanedicarboxylic acid, di(2-fluorophenyl) ester were tested against adults of vector mosquitoes Aedes aegypti and Culex quinquefasciatus of results were 84.82/168.78, 88.46/182.55, 92.30/174.63, 94.51/175.44, 96.42/174.84, 98.58/186.62 and 12.71/23.86, 11.23/22.82, 12.46/23.06, 12.34/23.37, 12.96/24.34, 12.89/23.85, 11.84/23.27, 12.36/23.79, 11.42/21.90, 11.34/21.93, 10.67/20.93 and 10.85/21.47 µg/ml, respectively. The outcomes of this present investigation well clearly indicated that the leaf methanol extracts of N. brachiata, L. crustacea and O. corniculata and its derived major phyto-compounds 1,4-Benzenedicarboxylic acid, bis(2-ethylhexyl) ester, Phthalic acid, hexadecyl 2,3,4,5-tetrafluorobenzyl ester, 2-Acetylamino-2-cyano-acetamide, Phosphorin, 2,4,6-tris(1,1-dimethylethyl)-, Succinic acid, 2-methylpent-3-yl pentafluorophenyl ester and 1,2-Cyclohexanedicarboxylic acid, di(2-fluorophenyl) ester had the potential effects on selected medical pests Ae. aegypti and Cx. quinquefasciatus. The findings of outputs as possible role battle with Ae. aegypti and C. quinquefasciatus. Further studies regarding the application selected phyto-products in the field application which will give the way for development of newer phyto-mosquitocide.